A 34-year-old woman was diagnosed with acute promyelocytic leukemia. Chemotherapy was administered following the JALSG\nAPL204 protocol. Induction therapy with all-trans retinoic acid resulted in complete remission on day 49. She developed\ncoccygeal pain from day 18, which spread to the spine and cheekbones and lasted 5 weeks. She had similar bone pain on days 7â??10\nof the first consolidation therapy and on days 4â??12 of the second consolidation therapy. Oral loxoprofen was prescribed for pain\nrelief. On day 33 of the third consolidation, white blood cell and neutrophil counts were ......................
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